What is the Collagenomics® series?


The Collagenomics® series is a collagen peptide that is rich in peptides that are stably and highly absorbed in the body after ingestion. The positive effects of oral ingestion of collagen peptide (or gelatin) have long been known. Collagen is a type of protein that was believed to be absorbed as an amino acid. In 2005,
a group led by Professor Kenji Sato of Kyoto Prefectural University (currently Kyoto University) found that orally ingested collagen peptides were not all absorbed as amino acids; some were detected in the blood
as peptides. This changed the way we think about protein nutrition. Furthermore, it has become clear that the peptides detected in the blood are Hyp-containing di- and tripeptides such as Pro-Hyp and
Ala-Hyp-Gly, and these functions have been reported one after another. At present, these are considered to be functional factors for the effect of oral intake of collagen peptide. Collagen peptides are generally made by breaking down collagen using proteolytic enzymes. Therefore, Nippi worked on the development of a manufacturing method that contains the active peptide, which is a functional factor, in advance. Due to severe restrictions on food manufacturing enzymes, it was difficult to produce the desired peptide, but thanks to the Nippi Research Institute of Biomatrix’s basic research results, it was commercialized as the Collagenomics® series. The peptides standardized in the Collagenomics® series are active peptides that are stable in the blood and can reach the required site.

Product Line-up

Ginger hydrolyzed collagen peptide

The ginger hydrolyzed collagen peptide series is manufactured using the proteolytic enzyme zingibain contained in ginger, and its manufacturing method has been patented in several countries including Japan, the United States, Canada, and China. We have standardized a high content of X-Hyp-Gly-type tripeptides, which are not included in conventional products. X-Hyp-Gly-type tripeptides are stable in blood and have been confirmed to be highly absorbable in mice and humans.

Dipeptide-rich collagen peptide

Dipeptide-rich collagen peptide is standardized with a high content of Pro-Hyp, which is most often detected in the blood after oral ingestion of collagen peptide. Increased Pro-Hyp content is expected to improve absorption into the blood after oral ingestion, compared with the conventional product. In addition, many physiological functions of Pro-Hyp have been reported, such as mesenchymal stem cell proliferation, improvement of brain function, wound healing, and improvement of bedsores.